托比，一个笨拙的OCD物理天才，和卡拉，一个炎热的前天主教女学生联谊会的女孩，醒来后，涂黑了万圣节的夜晚，发现他们错过了疏散地球。一个神秘的代理人追求长期不和的夫妇，因为他们想出了如何合作解决最近纠缠的多元宇宙和最终拯救人类。基于真实的科学，《天定命运向下:时空》将观众带入一段疯狂而荒谬的旅程，带他们进入量子力学和宗教世界，在那里两人最终达成了共识。这是一个古怪的“傻瓜物理学”，有了真实的教训，故事开始于CERN最近非常真实的发现，即所谓的“上帝粒子”——量子力学标准模型中缺失的一环。我们这个科学时代面临的最大挑战是，爱因斯坦的物理学——太阳系中的大天体——与小的粒子物理学没有联系，最终在我们对宇宙的认识中留下了巨大的鸿沟。因此，在过去的100年里，科学家们一直在拼命地寻找“万物理论”，这是一个将两种截然相反的关于我们的现实如何运作的理解联系在一起的等式。人们普遍认为上帝粒子是丢失的线索。全世界有数百万人关注每一个与这个主题相关的公告。这个故事和科学的核心是我们对时间的感知，对现实的幻觉，以及一个非常不合逻辑的概念，即我们所看到的并不是真的。
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