乔天生（陈展鹏饰）与罗威信（萧正楠饰）为一对同母异父的兄弟。天生原为香港人，后因父亲乔森（李国麟饰）撕毁出生证明书，两兄弟随着母亲回到佛山。1980年从佛山偷渡来香港，途中失散。哥哥天生独自来到香港，弟弟威信与妈妈周玉梅（李司棋饰）到了澳门，两兄弟怀着对生活的理想，各自在两地建立他们的事业，天生投考香港，威信则由小店主成为澳门饼店商人。经过港澳两地二十多年不同事件后，两兄弟的命运出现意想不到的逆转。天生在香港有一要好的女朋友卓静（钟嘉欣饰），惟卓静之母亲刘丽娟（谢雪心饰）是权贵失宠的三姨太，希望从此低调生活，女儿对天生的感情更深厚。丽娟有两个女儿，姊姊卓宁（李亚男饰）和妹妹卓静。卓静是一名时装设计师，天生为圆女友开设自己名牌的心愿，不惜与上流社会勾结，做出种种女友无法接受的事，包括与名流花比奥（贝安琪饰）发生亲密关系。相关新闻《巨轮》发布造型照 钟嘉欣与陈展鹏演情侣[3] 腾讯娱乐讯 无线新剧《巨轮》举行造型记者会，出席演员包括:钟嘉欣，陈展鹏，李亚男、萧正楠及田蕊妮等，为配合剧中九十年代的内容，众演员均以九十年代的造型亮相，陈展鹏更化身刘德华及郭富城两大天王的九十年代造型，唯肖唯妙。 《巨轮》主演造型图嘉欣记得自己九十年代大约七岁的时候，就於加拿大跟父母追看经典剧集《大时代》，今日她的发型也是十四岁时梳的款式，她更指自己的性格就一直停留在九十年代，很保守，所以很适合演这部剧。」戏中嘉欣首度与陈展鹏扮演情侣，更有亲热戏，但只是点到即止，嘉欣也很期待与展鹏合作。 陈展鹏首次与嘉欣演情侣，更指嘉欣是最想合作的无线女艺员，也很期待与对方拍亲热戏。说到他模仿天王的造型，他坦言是模仿刘德华及郭富城两大天王，但剧中并不是要模仿他们，只是反映现实年青人的打扮。钟嘉欣陈展鹏拍摄《巨轮》雨中激吻 钟嘉欣陈展鹏《巨轮》雨中激吻剧照钟嘉欣与陈展鹏前晚在尖东拍摄无线新剧《巨轮》。首次两人先在公园拍摄谈情戏，之后才拍摄下雨戏。该场戏是讲两人因为避雨，而走到电话亭暂避，两人因在狭窄的电话亭情深对望，继而便情不自禁的亲嘴。该场亲嘴戏也拍了两次，问两人事前有没有做好口腔清洁，嘉欣表示：“我有食香口胶。”见展鹏拍完第一次嘴时有点尴尬。两人之前也有试位，首先由陈展鹏先锡钟嘉欣面部，之后再嘴对嘴。更新
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