当一个神秘的包裹寄到他家的门阶上时，杰克·雷恩，DEA的前探员，立刻意识到有些事不大对劲。他发现包裹内包含他哥哥菲利浦对他发出的求助信号，是关于DEA在加勒比岛圣凯特的一项任务的。由于担心菲利浦会遇到生命危险，杰克不顾老板加兰的警告，他发誓要拯救哥哥。杰克不知道，菲利浦已经成为邪恶科学家琼清·凯瑟的
实验对象，这个实验会把人变成高科技电子杀手。 凯瑟的计划就是把这些先进的暗杀者卖给一个有钱的财团，这个财团正策划行刺圣凯特市的总统。到达加勒比岛后，杰克的行踪被凯瑟发现了，他想除掉杰克。杰克遇到了一个漂亮的女记者卡迪，她是来采访当地伏都教的。杰克把他的疑虑告诉她。意识到这里头大有文章可做，她答应帮助杰克寻找其哥哥。同时他们之间的关系亲密起来。参观过当地一个停尸房，他们发现那里有一些被剥去脸皮的尸体，他们担心菲利浦已遭毒手。 杰克和卡迪受到凯瑟手下的袭击，杰克杀死其中一人，但卡迪却被他们绑架了。在凯瑟的庄园里单独袭击凯瑟后，杰克发现了哥哥真正命运。经过一番激烈的搏斗，杰克唤醒了哥哥残存的人性意识，两兄弟合力把凯瑟压在桌下，救出卡迪，并救了总统一命。
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