在苏州长大的程子欣为了追随大学时期的男友来到北京，却被男友欺骗感情。伤心的子欣结识了金融才俊张申然和年轻建筑师方启宏。在申然的追求下，子欣尝试接受新感情，同时启宏发现子欣就是自己儿时在苏州的邻居。因身患阿兹海默症，启宏深知无法给子欣幸福，虽对子欣有意，启宏却只能将感情埋藏在心里，默默守护子欣。申然故友的妹妹露丝将申然的照顾误解为爱情，蓄意破坏申然与子欣的关系，导致二人因误会分手。再受情伤的子欣在启宏的带领和照顾下走出低谷。申然努力令露丝懂得占有不是真爱，露丝放手成全。误会终被澄清，申然希望与子欣重修旧好，子欣却发现自己爱上启宏，启宏却在此时不辞而别。原来启宏病情加重，不想拖累子欣，默默离开。面对情感抉择，子欣勇于追寻真爱。在申然祝福下，子欣选择守在启宏身边，陪他度过人生的最后时光。
大结局忘了全世界唯独记得你
张申然来见子欣和启宏，却发现启宏居然不认识他。启宏去画画之后，子欣告诉张申然，启宏得的是阿兹海默症。张申然非常吃惊，他没想到方启宏年纪轻轻竟然得的是这样的病，他更心疼子欣，要承受这么重的负担。张申然告诉子欣，郝杰在纽约组建了新公司，他要去帮他。说完，他一把抱住了子欣，两个人的内心都百感交集，却又无从…
子欣获悉启宏病情不离不弃
露丝以她过去苦苦单恋张申然的经历开导他，这个世界上，两情相悦本来就不是那么容易的事情，当爱一个人而不得的时候，不如选择放手。张申然想了许久，终于想通了，爱一个人就应该让她得到真正的幸福，不管自己对那个人有多么难以割舍。于是，他带子欣去找启宏。到了之后，子欣看见启宏就站在他们的房子前面，浇着花。看着这…
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张申然带子欣去了游乐场，俩人一起坐上了摩天轮。在摩天轮上，张申然突然告诉子欣，他要走了，去美国开分公司。子欣问他去多久，他说，说不好，也许一年，也许两年，也许更久。子欣问他，他们还会再见面吗？张申然反问她，她还想再见到他吗？见子欣对他的离开表现出不舍，他赶紧拿出戒指，单膝跪地向子欣求婚。他求子欣嫁给…
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