画心师岑欢因遭逢变故来到苍城，被中医铺子的宁为玉和司马空空救下。三人来到陆宅，结识了大小姐陆小曼与卫道人士九思，最终五人一起踏上了化人执念、解人心忧之途。在经历了一系列展现了人世间亲情、爱情、友情的故事后，他们终于感悟出：人生在世，遵守本心才是正途，邪魔外道终究会被正义打败。岑欢与宁为玉等人的感情日渐深重，他们也慢慢发现，自己所处的世界竟然只是一个梦境，而罪魁祸首，竟然就是妖兽转世的宁为玉和司马空空二人。最终，为了让世间的人醒来，不沉沦于梦境之中，他们选择牺牲了自己，唤醒了这个世界。
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妞妞奶奶看到孙女昏迷痛哭流涕，这时蒙面养心师突然出现，他说自己可以帮她不会让妞妞死，而妞妞病床边这时竟然出现三个无头鬼。 岑欢为了试探宁为玉是不是食梦貘，她故意灌醉了他。结果醉酒的宁为玉突然狂性大发力大无比地袭击了岑欢，岑欢根本不敌宁为玉。几招过后，宁为玉昏迷，岑欢也受伤。 次日晨宁为玉醒来，发…
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司马空空四处寻找宁为玉，这时小妖玉烟突然出现在司马空空身后，她告诉司马空空宁为玉被欧阳岚抓走。司马空空急忙让玉烟回济世堂找岑欢相助。 宁为玉醒来发现身处一个山洞，欧阳岚正冷笑着看着他。宁为玉非常不解他为什么把自己抓到山洞，欧阳岚称因为他帮助村民，宁为玉辩解称医者仁心救死扶伤为本分之事。欧阳岚这时突…
宁成玉遭遇妖怪酒颠童子
丹青把他和小柔凄美的感情讲给众人听，说完这些他已经是泪流满面，他跪求岑欢帮帮他们。岑欢分析所谓城西村遭马匪纵火屠村事实也许根本不是如此，极有可能是养心师故意杀人制造怨念。她说自己可以帮小柔化解心中的怨气和执念，也许她清醒后会痛苦，但远比现在神智不清要好。 在岑欢帮助下，小柔恢复心智。丹青决定带着小…
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