孟东东是一位失独母亲,不断试图和丈夫秦栓柱再要一个孩子。电台主播胡可嘉是孟家的儿媳,丈夫孟北方不顾她的事业危机要求她为孟家传宗接代,在胡可嘉决定先发展事业时得知父亲胡杰患癌症，她打算怀孕冲喜，孟北方发现因为自身生理问题，反逼胡可嘉闹离婚，胡可嘉以怪制怪保住了婚姻，胡父没有等到女儿怀孕遗憾离世；孟家老三夫妇是一对老少配,表面上两人很相爱,其实对外都不承认已婚,孟西西发现丈夫把财产留给前妻的女儿时,决定发起财富保卫战,但当她得知丈夫的女儿毛毛得了白血病，西西决定为挽救毛毛计划怀孕。孟东东想借卵生子，全家强烈反对，婚姻破裂，流浪儿豆芽使得孟东东夫妇重归于好，正当两人甜蜜幸福时，秦因救人发生意外。最终老三为毛毛配型成功生下孩子，老二也顺利产子，大姐建立儿童之家，救助流浪儿童。全家人聚在一起其乐融融。
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