雷蕾和罗永浩是大学里人人羡慕的一对情侣，两个人毕业后选择留在上海工作。罗永浩在雷蕾母亲沈曼逼迫下为了给雷蕾幸福，急切创业，却以惨败作为收尾。而雷蕾却在工作中凭着自己的实力得到了领导的赏识，她的晋升让她和罗永浩的经济实力变得愈发悬殊。女强男弱的格局让两人的相处变得举步维艰，罗永浩在自卑与自尊中徘徊挣扎...，再度选择创业，希望扭转两人的境况，然而急切渴望成功的心理让罗永浩再度失败。雷蕾母亲的压力、优秀追求者的出现，让两人的感情走向危机边缘。两个年轻人，在困顿中极力坚持爱和信任。
(大结局) 三年后，罗永浩成功了，一举成为著名的广告人，他也终于创办了自己的广告公司。 这天，罗永浩接到冯嘉人的电话，他邀请罗永浩来听他的音乐会，可没承想，邻座的居然是雷蕾。 演出结束后，雷蕾和罗永浩来到黄浦江边。罗永浩这才知道雷蕾一直单身，其实她早就知道罗永浩会有今天的成功，她一直耐心地等待，可…
雷蕾找王绮雯谈话，希望她退出。王绮雯明白自己是想从罗永浩身上寻求安慰，却也深深地明白罗永浩并不爱她。 罗永浩质问雷蕾跟王绮雯说了什么，并说王绮雯现在怀了他们的孩子，受不得刺激。雷蕾彻底崩溃了。
在沈曼的刺激下，罗永浩再也坐不住了，起身就走。并再次发短信向雷蕾提出分手。 公司体检，检查结果确定王绮雯怀孕了。王绮雯决定去打胎，罗永浩拿着化验单询问王绮雯，知道她怀孕，罗永浩决定负责任，要跟王绮雯结婚，两个人很快就办好了结婚证。 雷蕾从西安回上海，连夜去找罗永浩，却发现罗永浩和王绮雯在一起，深…
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